Patients treated for heartburn or indigestion continuously for ≥4 wk. History of gastric ulcer or stomach surgery. Patients >55 yr taking nonprescription indigestion treatment daily; w/ new or recently changed reflux symptoms. Patients due to have endoscopy, C-urea test, & Chromogranin A test. Concomitant use w/ HIV PIs; methotrexate. Risk of vit B
12 deficiency, symptomatic & asymptomatic hypomagnesemia, & osteoporosis-related fractures in long-term therapy. Monitor Mg levels prior to therapy & periodically. Increased risk of GI infections; subacute cutaneous lupus erythematosus (SCLE). May impair ability to drive & operate machines. Hepatic impairment or jaundice. Pregnancy & lactation. Childn & adolescents <18 yr.
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